Dorzolamide cautions include which iris change?

Dorzolamide cautions include which iris change?

• A. Iris darkening
• B. Iris pale
• C. Iris thinning
• D. Iris swelling

Answer: (A)

Dorzolamide is a topical carbonic anhydrase inhibitor used to lower intraocular pressure, and its cautions are mainly about sulfonamide allergy and potential local ocular side effects such as burning, stinging, and conjunctival hyperemia, with any systemic effects being rare. Iris pigment changes are not a typical caution with this drug. Iris darkening is a well-known pigment change associated with prostaglandin analog glaucoma meds (like latanoprost, bimatoprost, travoprost), caused by increased melanin in the iris stroma and is usually gradual and permanent, especially in lighter-colored irises. So, dorzolamide would not be expected to cause iris darkening; the iris color change described in this choice aligns with prostaglandin analogs, not with this medication.

Dorzolamide is a topical carbonic anhydrase inhibitor used to lower intraocular pressure, and its cautions are mainly about sulfonamide allergy and potential local ocular side effects such as burning, stinging, and conjunctival hyperemia, with any systemic effects being rare. Iris pigment changes are not a typical caution with this drug. Iris darkening is a well-known pigment change associated with prostaglandin analog glaucoma meds (like latanoprost, bimatoprost, travoprost), caused by increased melanin in the iris stroma and is usually gradual and permanent, especially in lighter-colored irises. So, dorzolamide would not be expected to cause iris darkening; the iris color change described in this choice aligns with prostaglandin analogs, not with this medication.